[PMID 18488026] 2,019 cases and 2,105 controls. Using pooling, we identified a new melanoma risk locus on chromosome 20 (rs910873 and rs1885120 combined P less than 1 10-15. The per allele odds ratio was 1.75 (1.53, 2.01), with evidence for stronger association in early-onset cases.
OMIM | 612263 |
Desc | MELANOMA, CUTANEOUS MALIGNANT, SUSCEPTIBILITY TO, 7; CMM7 |
Variant | |
Related | also |
[PMID 21221757] ASIP genetic variants and the number of non-melanoma skin cancers
[PMID 19578364] Genome-wide association study identifies three loci associated with melanoma risk.
[PMID 19995372] Melanoma susceptibility variants on chromosome 20q11.22 are associated with pigmentary traits and the risk of nonmelanoma skin cancer.
[PMID 20224305] Modest association of malignant melanoma with the rs910873 and rs1885120 markers on chromosome 20: a population-based study.
[PMID 23393597] Replication and Predictive Value of SNPs Associated with Melanoma and Pigmentation Traits in a Southern European Case-Control Study