rs1978331

Orientation

minus

Stabilized

minus

Make rs1978331(C;C)

Make rs1978331(C;T)

Make rs1978331(T;T)

Reference

GRCh38 38.1/141

Chromosome

12

Position

96015423

Gene

LTA4H

is a	snp
is	mentioned by
dbSNP	rs1978331
dbSNP (classic)	rs1978331
ClinGen	rs1978331
ebi	rs1978331
HLI	rs1978331
Exac	rs1978331
Gnomad	rs1978331
Varsome	rs1978331
LitVar	rs1978331
Map	rs1978331
PheGenI	rs1978331
Biobank	rs1978331
1000 genomes	rs1978331
hgdp	rs1978331
ensembl	rs1978331
geneview	rs1978331
scholar	rs1978331
google	rs1978331
pharmgkb	rs1978331
gwascentral	rs1978331
openSNP	rs1978331
23andMe	rs1978331
SNPshot	rs1978331
SNPdbe	rs1978331
MSV3d	rs1978331
GWAS Ctlg	rs1978331

GMAF

0.4711

Max Magnitude

0

?	(C;C) (C;T) (T;T)	28

[PMID 18547289] rs1978331 is one of several SNPs associated with asthma and allergy susceptibility based on a study of 341 Caucasian families.

OMIM	151570
Desc	LEUKOTRIENE A4 HYDROLASE; LTA4H
Variant
Related	also

[PMID 21308720] Associations between arachidonic acid metabolism gene polymorphisms and prostate cancer risk

OMIM	607948
Desc
Variant
Related	also

OMIM	609888
Desc
Variant
Related	also

[PMID 22206291] The role of ALOX5AP, LTA4H and LTB4R polymorphisms in determining baseline lung function and COPD susceptibility in UK smokers

[PMID 18187665] Identification of genetic polymorphisms associated with risk for pulmonary hypertension in sickle cell disease.

[PMID 19130089] Genetic effects in the leukotriene biosynthesis pathway and association with atherosclerosis.

[PMID 19665766] Genetics and pharmacogenetics of the leukotriene pathway.

[PMID 20401335] Sickle Cell Disease in the Post Genomic Era: A Monogenic Disease with a Polygenic Phenotype.

[PMID 21112816] Association analysis of the LTA4H gene polymorphisms and pulmonary tuberculosis in 9115 subjects.