rs2066853
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (G;G) | 0 |
| Make rs2066853(A;A) |
| Make rs2066853(A;G) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 7 |
| Position | 17339486 |
| Gene | AHR |
| is a | snp |
| is | mentioned by |
| dbSNP | rs2066853 |
| dbSNP (classic) | rs2066853 |
| ClinGen | rs2066853 |
| ebi | rs2066853 |
| HLI | rs2066853 |
| Exac | rs2066853 |
| Gnomad | rs2066853 |
| Varsome | rs2066853 |
| LitVar | rs2066853 |
| Map | rs2066853 |
| PheGenI | rs2066853 |
| Biobank | rs2066853 |
| 1000 genomes | rs2066853 |
| hgdp | rs2066853 |
| ensembl | rs2066853 |
| geneview | rs2066853 |
| scholar | rs2066853 |
| rs2066853 | |
| pharmgkb | rs2066853 |
| gwascentral | rs2066853 |
| openSNP | rs2066853 |
| 23andMe | rs2066853 |
| SNPshot | rs2066853 |
| SNPdbe | rs2066853 |
| MSV3d | rs2066853 |
| GWAS Ctlg | rs2066853 |
| GMAF | 0.2741 |
| Max Magnitude | 0 |
| ? | (A;A) (A;G) (G;G) | 28 |
|---|---|---|
|
| ||
rs2066853 has been associated with increased risk for colorectal polyps depending on the amount of meat eaten or overall exposure to heterocyclic amines. [PMID 18268115
]
[PMID 18818557] lung cancer in a Chinese population heterozygous rs2158041 OR=1.53 for GA vs compared with the (G;G) and rs7811989 OR=1.48 for (G;A) compared with the GG genotype)
- rs2066853 (p.Arg554Lys) and cumulative cigarette smoking and the Lys/Lys genotype conferred an increased risk of lung cancer in the heavy smokers OR=3.36
[PMID 19415745] Genetic polymorphisms of estrogen metabolizing enzyme and breast cancer risk in Thai women
[PMID 17160896] Orofacial cleft risk is increased with maternal smoking and specific detoxification-gene variants.
[PMID 18545700] Mitochondrial DNA haplogroup D4a is a marker for extreme longevity in Japan.
[PMID 18632753] Bladder cancer risk and genetic variation in AKR1C3 and other metabolizing genes.
[PMID 18805939] Functional genetic polymorphisms and female reproductive disorders: part II--endometriosis.
[PMID 18990750] Red meat intake, doneness, polymorphisms in genes that encode carcinogen-metabolizing enzymes, and colorectal cancer risk.
[PMID 22211302] The association of functional polymorphisms in the aryl hydrocarbon receptor (AHR) gene with the risk of vitiligo in Han Chinese populations.
[PMID 23168330] Genetic susceptibility to dioxin-like chemicals' induction of cytochrome P4501A2 in the human adult linked to specific AhRR polymorphism
[PMID 23528250] Genetic association of aromatic hydrocarbon receptor (AHR) and cytochrome P450, family 1, subfamily A, polypeptide 1 (CYP1A1) polymorphisms with dioxin blood concentrations among pregnant Japanese women
[PMID 23703535] Polymorphisms in Aryl Hydrocarbon Receptor Gene Are Associated With Idiopathic Male Factor Infertility
[PMID 22539616] Contributions of aryl hydrocarbon receptor genetic variants to the risk of glioma and PAH-DNA adducts.
[PMID 23492909] Pharmacogenetics of CYP1A2 activity and inducibility in smokers and exsmokers.
[PMID 28057405] Genetic variants associated with skin aging in the Chinese Han population.
[PMID 29325309] [Association of Crohn's disease with aryl hydrocarbon receptor gene polymorphisms and haplotypes].
