rs2077119
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (G;G) | 0.91x decreased risk for T2D | |
| (G;T) | 0.91x decreased risk for T2D | |
| (T;T) | 0 | 1x normal risk |
| Reference | GRCh38 38.1/141 |
| Chromosome | 3 |
| Position | 186612673 |
| Gene | AHSG |
| is a | snp |
| is | mentioned by |
| dbSNP | rs2077119 |
| dbSNP (classic) | rs2077119 |
| ClinGen | rs2077119 |
| ebi | rs2077119 |
| HLI | rs2077119 |
| Exac | rs2077119 |
| Gnomad | rs2077119 |
| Varsome | rs2077119 |
| LitVar | rs2077119 |
| Map | rs2077119 |
| PheGenI | rs2077119 |
| Biobank | rs2077119 |
| 1000 genomes | rs2077119 |
| hgdp | rs2077119 |
| ensembl | rs2077119 |
| geneview | rs2077119 |
| scholar | rs2077119 |
| rs2077119 | |
| pharmgkb | rs2077119 |
| gwascentral | rs2077119 |
| openSNP | rs2077119 |
| 23andMe | rs2077119 |
| SNPshot | rs2077119 |
| SNPdbe | rs2077119 |
| MSV3d | rs2077119 |
| GWAS Ctlg | rs2077119 |
| GMAF | 0.3792 |
| Max Magnitude | 0 |
| ? | (G;G) (G;T) (T;T) | 28 |
|---|---|---|
|
| ||
rs2077119, also known as -469T/G, is a SNP in the alpha-2-HS-glycoprotein AHSG gene.
In a study of ~3,800 Danish type-2 diabetes patients, pooled with a previous study, the minor rs2077119(G) allele showed a slight protective effect, with an odds ratio of 0.91 (CI: 0.84-0.99, p=0.007).[PMID 18316360]
[PMID 17889958] A promoter polymorphism of the alpha2-HS glycoprotein gene is associated with its transcriptional activity.
[PMID 22024217] Are AHSG polymorphisms directly associated with coronary atherosclerosis?
