||common in clinvar
|?|| (C;C) (C;G) (G;G) ||28|
|Desc||OROFACIAL CLEFT 6, SUSCEPTIBILITY TO; OFC6|
[PMID 19734457] Association between IRF6 SNPs and oral clefts in West China
[PMID 15558496] Strong evidence of linkage disequilibrium between polymorphisms at the IRF6 locus and nonsyndromic cleft lip with or without cleft palate, in an Italian population.
[PMID 17318851] Interferon regulatory factor 6 (IRF6) and fibroblast growth factor receptor 1 (FGFR1) contribute to human tooth agenesis.
[PMID 18278815] Genetic variants in IRF6 and the risk of facial clefts: single-marker and haplotype-based analyses in a population-based case-control study of facial clefts in Norway.
[PMID 20215007] Genetic control of individual differences in gene-specific methylation in human brain.
[PMID 28712851] IRF6 rs2235375 single nucleotide polymorphism is associated with isolated non-syndromic cleft palate but not with cleft lip with or without palate in south Indian population.