rs2241524 is a SNP in the LILRA2 gene that disrupts the splice acceptor site of intron 6.
Case-control association studies on 273 Japanese patients with systemic lupus erythematosus (SLE) and 50 patients with microscopic polyangiitis (MPA) showed an association between the homozygous rs2241524(T;T) genotype (as oriented in dbSNP). For the association with SLE, the odds ratio was 1.82 (CI: 1.02-3.24, p=0.041) and for MPA, the odds ratio was 2.52 (CI: 1.07-5.96, p=0.049).[PMID 18273033]
[PMID 17903297] Genetic correlates of brain aging on MRI and cognitive test measures: a genome-wide association and linkage analysis in the Framingham Study.
[PMID 20236493] The contribution of genetic variation and infection to the pathogenesis of ANCA-associated systemic vasculitis.