rs2283228
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (A;A) | 0 | common in complete genomics |
| Make rs2283228(A;C) |
| Make rs2283228(C;C) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 11 |
| Position | 2828300 |
| Gene | KCNQ1, LOC107987412 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs2283228 |
| dbSNP (classic) | rs2283228 |
| ClinGen | rs2283228 |
| ebi | rs2283228 |
| HLI | rs2283228 |
| Exac | rs2283228 |
| Gnomad | rs2283228 |
| Varsome | rs2283228 |
| LitVar | rs2283228 |
| Map | rs2283228 |
| PheGenI | rs2283228 |
| Biobank | rs2283228 |
| 1000 genomes | rs2283228 |
| hgdp | rs2283228 |
| ensembl | rs2283228 |
| geneview | rs2283228 |
| scholar | rs2283228 |
| rs2283228 | |
| pharmgkb | rs2283228 |
| gwascentral | rs2283228 |
| openSNP | rs2283228 |
| 23andMe | rs2283228 |
| SNPshot | rs2283228 |
| SNPdbe | rs2283228 |
| MSV3d | rs2283228 |
| GWAS Ctlg | rs2283228 |
| GMAF | 0.1804 |
| Max Magnitude | 0 |
| ? | (A;A) (A;C) (C;C) | 28 |
|---|---|---|
|
| ||
- rs2283228 (additive model P = 3.1 times 10-12; OR = 1.26, 95% CI = 1.18–1.34).
[PMID 19516902
] The type 2 diabetes associated minor allele of rs2237895 KCNQ1 associates with reduced insulin release following an oral glucose load
[PMID 19575309] Association study of four variants in KCNQ1 with type 2 diabetes mellitus and premature coronary artery disease in a Chinese population
[PMID 22479571] Several Polymorphisms of KCNQ1 Gene Are Associated with Plasma Lipid Levels in General Chinese Populations
[PMID 22206064] KCNQ1 variants associate with type 2 diabetes in Malaysian Malay subjects
[PMID 18711366] SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations.
[PMID 19252135] Genetic variation in KCNQ1 associates with fasting glucose and beta-cell function: a study of 3,734 subjects comprising three ethnicities living in Singapore.
[PMID 19448982] Variants in KCNQ1 are associated with susceptibility to type 2 diabetes in the population of mainland China.
[PMID 19502414] Association of 18 confirmed susceptibility loci for type 2 diabetes with indices of insulin release, proinsulin conversion, and insulin sensitivity in 5,327 nondiabetic Finnish men.
[PMID 20701788] KCNQ1 gene polymorphisms are associated with lipid parameters in a Chinese Han population.
[PMID 23271129] Meta-analysis of the effect of KCNQ1 gene polymorphism on the risk of type 2 diabetes
[PMID 23786590] Common Variants in KCNQ1 Confer Increased Risk of Type 2 Diabetes and Contribute to the Diabetic Epidemic in East Asians: A Replication and Meta-Analysis
[PMID 22696034] KCNQ1 SNPS and susceptibility to diabetic nephropathy in East Asians with type 2 diabetes.
[PMID 23107108] Lack of association between genetic polymorphisms within KCNQ1 locus and type 2 diabetes in Tunisian Arabs.
