||Increased risk of lung cancer in non-smokers and never smokers
news increased risk of lung cancer in non smokers. Analysis showed that the presence of this variant significantly increased the risk of a never smoker having lung cancer by 1.46 times (odds ratio 1.46, 95% confidence interval 1.26 to 1.70).
[PMID 20304703] Genetic variants and risk of lung cancer in never smokers: a genome-wide association study
[PMID 22236185] GPC5 rs2352028 Polymorphism and Risk of Lung Cancer in Han Chinese
[PMID 24456789] Variants in the 5'-upstream region of GPC5 confer risk of lung cancer in never smokers
[PMID 23297363] Genome-wide association study identifies loci on 12q24 and 13q32 associated with tetralogy of Fallot.