rs25531(A;A)
From SNPedia
| short form of 5-HTTLPR. lower levels of serotonin, slightly less happy, benefits from more support |
| Is a | genotype |
| of | rs25531 |
| Gene | SLC6A4, LOC105371720 |
| Chromosome | 17 |
| Position | 30,237,328 |
| mentioned | by |
| Magnitude | 2.5 |
| Geno | Mag | Summary |
|---|---|---|
| (-;-) | ||
| (A;A) | 2.5 | short form of 5-HTTLPR. lower levels of serotonin, slightly less happy, benefits from more support |
| (G;G) | 2.1 | long form of 5-HTTLPR. less sensitive to pain |
23andMe reports that this genotype is not reliable on their platform. 23andMe users should ignore this result.
This genotype is associated with lower levels of serotonin and appears to have a cognitive effect related to emotions, but the effect is slight and no one in SNPedia has yet found a good description. However the (G;G) genotype generally seems to have more positive associations, while this (A;A) is more negative. Examples of the differences include biased attention for negative word stimuli and gaze bias for emotional information.
More reluctant to endorse utilitarian actions resulting in foreseen harm to an innocent individual 10.1371/journal.pone.0025148
The genotype of this SNP is not meaningful on 23andme v3.
