rs27388
From SNPedia
Orientation | plus |
Stabilized | plus |
Geno | Mag | Summary |
---|---|---|
(A;A) | 2 | Increased risk of developing schizophrenia |
(A;G) | 1.5 | Slightly increased risk of developing schizophrenia |
(G;G) | 1 | Normal risk of developing schizophrenia |
Reference | GRCh38 38.1/141 |
Chromosome | 5 |
Position | 127348117 |
Gene | MEGF10 |
is a | snp |
is | mentioned by |
dbSNP | rs27388 |
dbSNP (classic) | rs27388 |
ClinGen | rs27388 |
ebi | rs27388 |
HLI | rs27388 |
Exac | rs27388 |
Gnomad | rs27388 |
Varsome | rs27388 |
LitVar | rs27388 |
Map | rs27388 |
PheGenI | rs27388 |
Biobank | rs27388 |
1000 genomes | rs27388 |
hgdp | rs27388 |
ensembl | rs27388 |
geneview | rs27388 |
scholar | rs27388 |
rs27388 | |
pharmgkb | rs27388 |
gwascentral | rs27388 |
openSNP | rs27388 |
23andMe | rs27388 |
SNPshot | rs27388 |
SNPdbe | rs27388 |
MSV3d | rs27388 |
GWAS Ctlg | rs27388 |
GMAF | 0.4959 |
Max Magnitude | 2 |
? | (A;A) (A;G) (G;G) | 28 |
---|---|---|
|
rs27388 is a SNP in the MEGF10 gene.
In a case-control study involving 652 Irish patients, rs27388(A) allele carriers were at increased risk for schizophrenia. (Note that the (A) allele is quite common in many populations.)[PMID 18179784]
[PMID 20813413] No association between schizophrenia and rs27388 of the MEGF10 gene in Chinese case-control sample.