Have questions? Visit https://www.reddit.com/r/SNPedia

rs27388

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A) 2 Increased risk of developing schizophrenia
(A;G) 1.5 Slightly increased risk of developing schizophrenia
(G;G) 1 Normal risk of developing schizophrenia
ReferenceGRCh38 38.1/141
Chromosome5
Position127348117
GeneMEGF10
is asnp
is mentioned by
dbSNPrs27388
dbSNP (classic)rs27388
ClinGenrs27388
ebirs27388
HLIrs27388
Exacrs27388
Gnomadrs27388
Varsomers27388
LitVarrs27388
Maprs27388
PheGenIrs27388
Biobankrs27388
1000 genomesrs27388
hgdprs27388
ensemblrs27388
geneviewrs27388
scholarrs27388
googlers27388
pharmgkbrs27388
gwascentralrs27388
openSNPrs27388
23andMers27388
SNPshotrs27388
SNPdbers27388
MSV3drs27388
GWAS Ctlgrs27388
GMAF0.4959
Max Magnitude2
? (A;A) (A;G) (G;G) 28


rs27388 is a SNP in the MEGF10 gene.

In a case-control study involving 652 Irish patients, rs27388(A) allele carriers were at increased risk for schizophrenia. (Note that the (A) allele is quite common in many populations.)[PMID 18179784OA-icon.png]

[PMID 20813413] No association between schizophrenia and rs27388 of the MEGF10 gene in Chinese case-control sample.