rs276174842

plus

Geno	Mag	Summary
(-;-)	0	common in clinvar
(-;TT)	6	BRCA2 variant considered pathogenic for breast cancer

Make rs276174842(TT;TT)

Reference

GRCh38 38.1/142

Chromosome

13

Position

32338493

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs276174842
dbSNP (classic)	rs276174842
ClinGen	rs276174842
ebi	rs276174842
HLI	rs276174842
Exac	rs276174842
Gnomad	rs276174842
Varsome	rs276174842
LitVar	rs276174842
Map	rs276174842
PheGenI	rs276174842
Biobank	rs276174842
1000 genomes	rs276174842
hgdp	rs276174842
ensembl	rs276174842
geneview	rs276174842
scholar	rs276174842
google	rs276174842
pharmgkb	rs276174842
gwascentral	rs276174842
openSNP	rs276174842
23andMe	rs276174842
SNPshot	rs276174842
SNPdbe	rs276174842
MSV3d	rs276174842
GWAS Ctlg	rs276174842

Merged from

Rs397507709

Max Magnitude

6

rs276174842, also known as 4366insTT, c.4138_4139insTT, c.4139_4140dupTT and p.Ile1380?fs, is a variant in the BRCA2 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs276174842(TT;TT)
Alt	rs276174842(TT;TT)
Reference	Rs276174842(-;-)
Significance	Pathogenic
Disease	Familial cancer of breast Breast-ovarian cancer Hereditary cancer-predisposing syndrome not provided
Variation	info
Gene	BRCA2
CLNDBN	Familial cancer of breast Breast-ovarian cancer, familial 2 Hereditary cancer-predisposing syndrome not provided
Reversed	0
HGVS	NC_000013.10:g.32912631_32912632dupTT
CLNSRC	Breast Cancer Information Core (BRCA2)
CLNACC	RCV000044359.2, RCV000113279.2, RCV000130775.2, RCV000483206.2,