rs2802288
Orientation | plus |
Stabilized | plus |
Geno | Mag | Summary |
---|---|---|
(A;A) | 2.4 | longer lifespan |
(A;G) | ||
(G;G) | 0 | normal |
Reference | GRCh38 38.1/141 |
Chromosome | 6 |
Position | 108575012 |
Gene | FOXO3 |
is a | snp |
is | mentioned by |
dbSNP | rs2802288 |
dbSNP (classic) | rs2802288 |
ClinGen | rs2802288 |
ebi | rs2802288 |
HLI | rs2802288 |
Exac | rs2802288 |
Gnomad | rs2802288 |
Varsome | rs2802288 |
LitVar | rs2802288 |
Map | rs2802288 |
PheGenI | rs2802288 |
Biobank | rs2802288 |
1000 genomes | rs2802288 |
hgdp | rs2802288 |
ensembl | rs2802288 |
geneview | rs2802288 |
scholar | rs2802288 |
rs2802288 | |
pharmgkb | rs2802288 |
gwascentral | rs2802288 |
openSNP | rs2802288 |
23andMe | rs2802288 |
SNPshot | rs2802288 |
SNPdbe | rs2802288 |
MSV3d | rs2802288 |
GWAS Ctlg | rs2802288 |
GMAF | 0.4486 |
Max Magnitude | 2.4 |
? | (A;A) (A;G) (G;G) | 28 |
---|---|---|
|
23andMe blog longevity rs2802288(A) increased the odds of living to 100 by 1.5x. rs2802288 is located very close to rs2802292 which was previously reported to have a similar effect.
[PMID 18978678] Candidate gene/loci studies in cleft lip/palate and dental anomalies finds novel susceptibility genes for clefts.
[PMID 19196970] Association of FOXO3A variation with human longevity confirmed in German centenarians.
[PMID 19415983] Association of the FOXO3A locus with extreme longevity in a southern Italian centenarian study.
[PMID 32975901] Genetic variability in 13q33 and 9q34 is linked to Aggressiveness Patterns and a Higher risk of progression of Non-Muscle-Invasive Bladder Cancer at the time of Diagnosis.