Have questions? Visit https://www.reddit.com/r/SNPedia

rs2837960

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(G;G) 2.3 2.3x rheumatoid arthritis risk
(G;T) 0 normal
(T;T) 0 normal
ReferenceGRCh38 38.1/141
Chromosome21
Position41139991
GeneLINC00323
is asnp
is mentioned by
dbSNPrs2837960
dbSNP (classic)rs2837960
ClinGenrs2837960
ebirs2837960
HLIrs2837960
Exacrs2837960
Gnomadrs2837960
Varsomers2837960
LitVarrs2837960
Maprs2837960
PheGenIrs2837960
Biobankrs2837960
1000 genomesrs2837960
hgdprs2837960
ensemblrs2837960
geneviewrs2837960
scholarrs2837960
googlers2837960
pharmgkbrs2837960
gwascentralrs2837960
openSNPrs2837960
23andMers2837960
SNPshotrs2837960
SNPdbers2837960
MSV3drs2837960
GWAS Ctlgrs2837960
GMAF0.2071
Max Magnitude2.3
? (G;G) (G;T) (T;T) 28


rs2837960 has been reported in a large study to be associated with rheumatoid arthritis.

The risk allele (oriented to the dbSNP entry) is (G); the odds ratio associated with heterozygotes is 0.95 (CI 0.83-1.08), and for homozygotes, 2.30 (CI 1.64-3.23). [PMID 17554300OA-icon.png]

GWAS
SNP rs2837960
PubMedID [PMID 17554300OA-icon.png]
Condition Rheumatoid arthritis
Gene NR
Risk Allele G
pValue 2.00E-006
OR 1.05
95% CI 0.93-1.20



[PMID 21595938OA-icon.png] Rheumatoid arthritis-associated polymorphisms are not protective against Alzheimer's disease

[PMID 18794857OA-icon.png] Rheumatoid arthritis susceptibility loci at chromosomes 10p15, 12q13 and 22q13.

[PMID 20017963OA-icon.png] Representation of genetic association via attributable familial relative risks in order to identify polymorphisms functionally relevant to rheumatoid arthritis.

[PMID 20426808OA-icon.png] AntEpiSeeker: detecting epistatic interactions for case-control studies using a two-stage ant colony optimization algorithm.