rs2837960
Orientation | plus |
Stabilized | plus |
Geno | Mag | Summary |
---|---|---|
(G;G) | 2.3 | 2.3x rheumatoid arthritis risk |
(G;T) | 0 | normal |
(T;T) | 0 | normal |
Reference | GRCh38 38.1/141 |
Chromosome | 21 |
Position | 41139991 |
Gene | LINC00323 |
is a | snp |
is | mentioned by |
dbSNP | rs2837960 |
dbSNP (classic) | rs2837960 |
ClinGen | rs2837960 |
ebi | rs2837960 |
HLI | rs2837960 |
Exac | rs2837960 |
Gnomad | rs2837960 |
Varsome | rs2837960 |
LitVar | rs2837960 |
Map | rs2837960 |
PheGenI | rs2837960 |
Biobank | rs2837960 |
1000 genomes | rs2837960 |
hgdp | rs2837960 |
ensembl | rs2837960 |
geneview | rs2837960 |
scholar | rs2837960 |
rs2837960 | |
pharmgkb | rs2837960 |
gwascentral | rs2837960 |
openSNP | rs2837960 |
23andMe | rs2837960 |
SNPshot | rs2837960 |
SNPdbe | rs2837960 |
MSV3d | rs2837960 |
GWAS Ctlg | rs2837960 |
GMAF | 0.2071 |
Max Magnitude | 2.3 |
? | (G;G) (G;T) (T;T) | 28 |
---|---|---|
|
rs2837960 has been reported in a large study to be associated with rheumatoid arthritis.
The risk allele (oriented to the dbSNP entry) is (G); the odds ratio associated with heterozygotes is 0.95 (CI 0.83-1.08), and for homozygotes, 2.30 (CI 1.64-3.23). [PMID 17554300]
GWAS | |
---|---|
SNP | rs2837960 |
PubMedID | [PMID 17554300] |
Condition | Rheumatoid arthritis |
Gene | NR |
Risk Allele | G |
pValue | 2.00E-006 |
OR | 1.05 |
95% CI | 0.93-1.20 |
[PMID 21595938] Rheumatoid arthritis-associated polymorphisms are not protective against Alzheimer's disease
[PMID 18794857] Rheumatoid arthritis susceptibility loci at chromosomes 10p15, 12q13 and 22q13.
[PMID 20017963] Representation of genetic association via attributable familial relative risks in order to identify polymorphisms functionally relevant to rheumatoid arthritis.
[PMID 20426808] AntEpiSeeker: detecting epistatic interactions for case-control studies using a two-stage ant colony optimization algorithm.