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rs307377

From SNPedia

umami taste sensitivity
Orientationplus
Stabilizedplus
Geno Mag Summary
(C;C) 0 common in complete genomics
(C;T) 2.4 extra tasting ability?
(T;T) 2.6 extra tasting ability?
ReferenceGRCh38 38.1/141
Chromosome1
Position1334174
GeneTAS1R3
is asnp
is mentioned by
dbSNPrs307377
dbSNP (classic)rs307377
ClinGenrs307377
ebirs307377
HLIrs307377
Exacrs307377
Gnomadrs307377
Varsomers307377
LitVarrs307377
Maprs307377
PheGenIrs307377
Biobankrs307377
1000 genomesrs307377
hgdprs307377
ensemblrs307377
geneviewrs307377
scholarrs307377
googlers307377
pharmgkbrs307377
gwascentralrs307377
openSNPrs307377
23andMers307377
SNPshotrs307377
SNPdbers307377
MSV3drs307377
GWAS Ctlgrs307377
GMAF0.0404
Max Magnitude2.6

Influences tasting ability.

This blog entry discusses the research.

[PMID 19587085OA-icon.png] the rare T allele of rs307377(T) (R757C) in TAS1R3 led to a doubling of umami ratings of 25 mmol MPG/L. Other suggestive SNPs of TAS1R3 include the A allele of A5T and the A allele of R247H, which both resulted in an approximate doubling of umami ratings of 200 mmol MPG/L


[PMID 16782140OA-icon.png] Diverse tastes: Genetics of sweet and bitter perception.


[PMID 19092995OA-icon.png] Bitter taste receptors influence glucose homeostasis.


[PMID 19696921OA-icon.png] Genetic and molecular basis of individual differences in human umami taste perception.