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rs3747742

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(G;G) 2
Make rs3747742(C;C)
Make rs3747742(C;T)
Make rs3747742(T;T)
ReferenceGRCh38 38.1/141
Chromosome6
Position41194780
GeneTREML2
is asnp
is mentioned by
dbSNPrs3747742
dbSNP (classic)rs3747742
ClinGenrs3747742
ebirs3747742
HLIrs3747742
Exacrs3747742
Gnomadrs3747742
Varsomers3747742
LitVarrs3747742
Maprs3747742
PheGenIrs3747742
Biobankrs3747742
1000 genomesrs3747742
hgdprs3747742
ensemblrs3747742
geneviewrs3747742
scholarrs3747742
googlers3747742
pharmgkbrs3747742
gwascentralrs3747742
openSNPrs3747742
23andMers3747742
SNPshotrs3747742
SNPdbers3747742
MSV3drs3747742
GWAS Ctlgrs3747742
Max Magnitude2
? (C;C) (C;T) (T;T) 28


rs3747742 is a SNP in the Triggering receptor expressed on myeloid cells-like 2 TREML2 gene.

See the genotype page rs3747742(G;G).

The minor allele of rs3747742 has been reported in a large study (IGAP) to be associated with a reduced risk of Alzheimer's Disease. The protective allele is (G). The odds ratio associated with heterozygotes and homozygotes of the G allele versus the A allele is 0.93 (CI 0.89-0.96). [PMID 24439484OA-icon.png] Missense variant in TREML2 protects against Alzheimer's disease