Have questions? Visit https://www.reddit.com/r/SNPedia

rs3794260

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A) >1.26x risk for hypertension
(A;G) 1.26x risk for hypertension
(G;G) 0 average
ReferenceGRCh38 38.1/141
Chromosome12
Position108204497
GeneLOC105369965, WSCD2
is asnp
is mentioned by
dbSNPrs3794260
dbSNP (classic)rs3794260
ClinGenrs3794260
ebirs3794260
HLIrs3794260
Exacrs3794260
Gnomadrs3794260
Varsomers3794260
LitVarrs3794260
Maprs3794260
PheGenIrs3794260
Biobankrs3794260
1000 genomesrs3794260
hgdprs3794260
ensemblrs3794260
geneviewrs3794260
scholarrs3794260
googlers3794260
pharmgkbrs3794260
gwascentralrs3794260
openSNPrs3794260
23andMers3794260
SNPshotrs3794260
SNPdbers3794260
MSV3drs3794260
GWAS Ctlgrs3794260
GMAF0.04683
Max Magnitude0
? (A;A) (A;G) (G;G) 28


rs3794260, a SNP in the KIAA0789 gene, was associated with risk for hypertension in a study involving 1,500+ Japanese patients. The odds ratio associated with the risk allele, rs3794260(G), which is also the most common allele, is 1.26 (CI: 1.12 - 1.42, p = 0.0001). [PMID 18003638]

Note that another SNP in the KIAA0789 gene, rs9739493, was determined to be in a different linkage disequilibrium block, and is thus thought to be an independent risk factor for hypertension. [PMID 18003638]