rs3816587
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | 1.3x risk | |
| (C;T) | 0 | normal |
| (T;T) | 0 | normal |
| Reference | GRCh38 38.1/141 |
| Chromosome | 4 |
| Position | 25415622 |
| Gene | ANAPC4 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs3816587 |
| dbSNP (classic) | rs3816587 |
| ClinGen | rs3816587 |
| ebi | rs3816587 |
| HLI | rs3816587 |
| Exac | rs3816587 |
| Gnomad | rs3816587 |
| Varsome | rs3816587 |
| LitVar | rs3816587 |
| Map | rs3816587 |
| PheGenI | rs3816587 |
| Biobank | rs3816587 |
| 1000 genomes | rs3816587 |
| hgdp | rs3816587 |
| ensembl | rs3816587 |
| geneview | rs3816587 |
| scholar | rs3816587 |
| rs3816587 | |
| pharmgkb | rs3816587 |
| gwascentral | rs3816587 |
| openSNP | rs3816587 |
| 23andMe | rs3816587 |
| SNPshot | rs3816587 |
| SNPdbe | rs3816587 |
| MSV3d | rs3816587 |
| GWAS Ctlg | rs3816587 |
| GMAF | 0.4683 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
rs3816587 has been reported in a large study to be associated with rheumatoid arthritis.
The risk allele (oriented to the dbSNP entry) is (C); the odds ratio associated with heterozygotes is 0.91 (CI 0.80-1.04), and for homozygotes, 1.35 (CI 1.14-1.59). [PMID 17554300
]
| GWAS | |
|---|---|
| SNP | rs3816587 |
| PubMedID | [PMID 17554300]
|
| Condition | Rheumatoid arthritis |
| Gene | NR |
| Risk Allele | C |
| pValue | 9.00E-006 |
| OR | 1.09 |
| 95% CI | 0.96-1.25 |
[PMID 18794857] Rheumatoid arthritis susceptibility loci at chromosomes 10p15, 12q13 and 22q13.
[PMID 20017963] Representation of genetic association via attributable familial relative risks in order to identify polymorphisms functionally relevant to rheumatoid arthritis.
