rs4146894(A;A)
From SNPedia
| 9.1x risk for AMD, but replication is lacking |
| Is a | genotype |
| of | rs4146894 |
| Gene | PLEKHA1 |
| Chromosome | 10 |
| Position | 122,395,865 |
| mentioned | by |
| Magnitude | 2.1 |
| Geno | Mag | Summary |
|---|---|---|
| (A;A) | 2.1 | 9.1x risk for AMD, but replication is lacking |
| (A;G) | 2.6x risk for AMD | |
| (G;G) | 0 | average |
A study in 2007 identified this and two other variants (rs10490924 and rs11200638) as indicating a 9x risk of age related macular degeneration. The other two snps are now well replicated, but replications of the snp you have are still lacking.
