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rs42490

From SNPedia

Orientationplus
Stabilizedplus
Make rs42490(A;A)
Make rs42490(A;G)
Make rs42490(G;G)
ReferenceGRCh38 38.1/141
Chromosome8
Position89766285
GeneRIPK2
is asnp
is mentioned by
dbSNPrs42490
dbSNP (classic)rs42490
ClinGenrs42490
ebirs42490
HLIrs42490
Exacrs42490
Gnomadrs42490
Varsomers42490
LitVarrs42490
Maprs42490
PheGenIrs42490
Biobankrs42490
1000 genomesrs42490
hgdprs42490
ensemblrs42490
geneviewrs42490
scholarrs42490
googlers42490
pharmgkbrs42490
gwascentralrs42490
openSNPrs42490
23andMers42490
SNPshotrs42490
SNPdbers42490
MSV3drs42490
GWAS Ctlgrs42490
GMAF0.4343
Max Magnitude0
? (A;A) (A;G) (G;G) 28


Variant in the RIPK2 gene associated with a reduced risk of leprosy in Asians, according to the 23andMe blog. The protective allele is A, and the odds ratio is 0.76.

GWAS snp
PMID [PMID 20018961]
Trait Leprosy
Title Genomewide Association Study of Leprosy
Risk Allele G
P-val 1E-16
Odds Ratio 1.32 [1.23-1.41]


[PMID 22504414] Association between C13ORF31, NOD2, RIPK2 and TLR10 polymorphisms and urothelial bladder cancer.


Leprosy Susceptibility