Geno
|
Mag
|
Summary
|
(A;A)
|
0
|
normal/common in clinvar
|
(A;G)
|
1.2
|
slight increase in risk for psoriatic arthritis
|
(G;G)
|
1.4
|
slight increase in risk for psoriatic arthritis
|
[PMID 25651891] reports rs4795067, with risk/non-risk alleles G/A, has an odds ratio of 1.2 (p=2e−7) for psoriatic arthritis based on a case/control study of ~2,000 patients.
GWAS snp
|
PMID
|
[PMID 20953189]
|
Trait
|
|
Title
|
Genome-wide association and anaylsis identifies three psoriasis susceptibility loci
|
Risk Allele
|
G
|
P-val
|
4E-11
|
Odds Ratio
|
1.1900 [NR]
|
[PMID 18663495] Nitric oxide synthase genes and their interactions with environmental factors in Parkinson's disease.
[PMID 19505917] Lead exposure, polymorphisms in genes related to oxidative stress, and risk of adult brain tumors.
[PMID 24323870] Genetic Association Analyses of Nitric Oxide Synthase Genes and Neural Tube Defects Vary by Phenotype