rs4963128
| Orientation | minus |
| Stabilized | minus |
| Geno | Mag | Summary |
|---|---|---|
| (G;G) | 0 | common in complete genomics |
| Make rs4963128(A;A) |
| Make rs4963128(A;G) |
| Reference | GRCh37 37.1/131 |
| Chromosome | 11 |
| Position | 589564 |
| Gene | PHRF1 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs4963128 |
| dbSNP (classic) | rs4963128 |
| ClinGen | rs4963128 |
| ebi | rs4963128 |
| HLI | rs4963128 |
| Exac | rs4963128 |
| Gnomad | rs4963128 |
| Varsome | rs4963128 |
| LitVar | rs4963128 |
| Map | rs4963128 |
| PheGenI | rs4963128 |
| Biobank | rs4963128 |
| 1000 genomes | rs4963128 |
| hgdp | rs4963128 |
| ensembl | rs4963128 |
| geneview | rs4963128 |
| scholar | rs4963128 |
| rs4963128 | |
| pharmgkb | rs4963128 |
| gwascentral | rs4963128 |
| openSNP | rs4963128 |
| 23andMe | rs4963128 |
| SNPshot | rs4963128 |
| SNPdbe | rs4963128 |
| MSV3d | rs4963128 |
| GWAS Ctlg | rs4963128 |
| GMAF | 0.2966 |
| Max Magnitude | 0 |
| ? | (A;A) (A;G) (G;G) | 28 |
|---|---|---|
|
| ||
| GWAS | |
|---|---|
| SNP | rs4963128 |
| PubMedID | [PMID 18204446 ]
|
| Condition | Systemic lupus erythematosus in women |
| Gene | KIAA1542 |
| Risk Allele | |
| pValue | 3.00E-010 |
| OR | 1.28 |
| 95% CI | 1.18-1.37 |
[PMID 19714582] Rheumatoid arthritis does not share most of the newly identified systemic lupus erythematosus genetic factors
[PMID 20112359] Genetic variation at the IRF7/PHRF1 locus is associated with autoantibody profile and serum interferon-alpha activity in lupus patients
[PMID 21165897] Association of a functional IRF7 variant with systemic lupus erythematosus
| GWAS snp | |
|---|---|
| PMID | [PMID 21408207]
|
| Trait | |
| Title | Differential Genetic Associations for Systemic Lupus Erythematosus Based on Anti-dsDNA Autoantibody Production |
| Risk Allele | |
| P-val | 0.000004 |
| Odds Ratio | 1.3300 [1.18-1.49] |
[PMID 18853133] Gene variants influencing measures of inflammation or predisposing to autoimmune and inflammatory diseases are not associated with the risk of type 2 diabetes.
[PMID 19442287] Replication of recently identified systemic lupus erythematosus genetic associations: a case-control study.
[PMID 19838195] A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus.
[PMID 21167895] Association of genetic variations in the STAT4 and IRF7/KIAA1542 regions with systemic lupus erythematosus in a Northern Han Chinese population.
[PMID 21360504] Association of a functional IRF7 variant with systemic lupus erythematosus.
[PMID 21379322] Risk alleles for systemic lupus erythematosus in a large case-control collection and associations with clinical subphenotypes.
[PMID 21926187] Novel identification of the IRF7 region as an anticentromere autoantibody propensity locus in systemic sclerosis.
[PMID 22433914] Association of PHRF1-IRF7 region polymorphism with clinical manifestations of systemic lupus erythematosus in a Japanese population.
