rs4988300

plus

Geno	Mag	Summary
(G;T)

Make rs4988300(G;G)

Make rs4988300(T;T)

Reference

GRCh38 38.1/141

Chromosome

11

Position

68321363

Gene

LRP5

is a	snp
is	mentioned by
dbSNP	rs4988300
dbSNP (classic)	rs4988300
ClinGen	rs4988300
ebi	rs4988300
HLI	rs4988300
Exac	rs4988300
Gnomad	rs4988300
Varsome	rs4988300
LitVar	rs4988300
Map	rs4988300
PheGenI	rs4988300
Biobank	rs4988300
1000 genomes	rs4988300
hgdp	rs4988300
ensembl	rs4988300
geneview	rs4988300
scholar	rs4988300
google	rs4988300
pharmgkb	rs4988300
gwascentral	rs4988300
openSNP	rs4988300
23andMe	rs4988300
SNPshot	rs4988300
SNPdbe	rs4988300
MSV3d	rs4988300
GWAS Ctlg	rs4988300

GMAF

0.4311

Max Magnitude

0

?

(G;G) (G;T) (T;T)

28

linked to obesity

OMIM	603506
Desc	LOW DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 5; LRP5
Variant
Related	also

[PMID 16723389 ] Polymorphisms of the low-density lipoprotein receptor-related protein 5 (LRP5) gene are associated with obesity phenotypes in a large family-based association study.

[PMID 17002564 ] Robust and comprehensive analysis of 20 osteoporosis candidate genes by very high-density single-nucleotide polymorphism screen among 405 white nuclear families identified significant association and gene-gene interaction.

[PMID 17903296 ] Genome-wide association with bone mass and geometry in the Framingham Heart Study.

[PMID 18455228 ] Bone mineral density, osteoporosis, and osteoporotic fractures: a genome-wide association study.

[PMID 25762437] Strong effect of SNP rs4988300 of the LRP5 gene on bone phenotype of Caucasian postmenopausal women