rs515726091

Orientation

plus

Stabilized

plus

Geno	Mag	Summary
(-;-)	0	common in clinvar
(-;A)	3	2-4 fold higher risk for breast cancer, depending on family history
(A;A)	7	Fanconi anemia, complementation group N

Reference

GRCh38 38.1/141

Chromosome

16

Position

23626298

Gene

PALB2

is a	snp
is	mentioned by
dbSNP	rs515726091
dbSNP (classic)	rs515726091
ClinGen	rs515726091
ebi	rs515726091
HLI	rs515726091
Exac	rs515726091
Gnomad	rs515726091
Varsome	rs515726091
LitVar	rs515726091
Map	rs515726091
PheGenI	rs515726091
Biobank	rs515726091
1000 genomes	rs515726091
hgdp	rs515726091
ensembl	rs515726091
geneview	rs515726091
scholar	rs515726091
google	rs515726091
pharmgkb	rs515726091
gwascentral	rs515726091
openSNP	rs515726091
23andMe	rs515726091
SNPshot	rs515726091
SNPdbe	rs515726091
MSV3d	rs515726091
GWAS Ctlg	rs515726091

Merged from

Rs180177121

Max Magnitude

7

[PMID 25099575] Breast-Cancer Risk in Families with Mutations in PALB2

see also ClinVar (where clinical significance = pathogenic)

ClinVar
Risk	Rs515726091(A;A)
Alt	Rs515726091(A;A)
Reference	Rs515726091(-;-)
Significance	Pathogenic
Disease	Familial cancer of breast not provided
Variation	info
Gene	PALB2
CLNDBN	Familial cancer of breast not provided
Reversed	0
HGVS	NC_000016.9:g.23637619dupA
CLNSRC	PALB2 database
CLNACC	RCV000114550.1, RCV000486793.1,