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rs594242

From SNPedia

Orientationminus
Stabilizedminus
Geno Mag Summary
(C;G)
Make rs594242(C;C)
Make rs594242(G;G)
ReferenceGRCh38 38.1/141
Chromosome13
Position46883917
GeneHTR2A
is asnp
is mentioned by
dbSNPrs594242
dbSNP (classic)rs594242
ClinGenrs594242
ebirs594242
HLIrs594242
Exacrs594242
Gnomadrs594242
Varsomers594242
LitVarrs594242
Maprs594242
PheGenIrs594242
Biobankrs594242
1000 genomesrs594242
hgdprs594242
ensemblrs594242
geneviewrs594242
scholarrs594242
googlers594242
pharmgkbrs594242
gwascentralrs594242
openSNPrs594242
23andMers594242
SNPshotrs594242
SNPdbers594242
MSV3drs594242
GWAS Ctlgrs594242
GMAF0.1299
Max Magnitude0
? (C;C) (C;G) (G;G) 28


[PMID 16814396] Three (rs643627-rs594242-rs6311: A-C-T), two (rs594242-rs6311: C-T) and a single functional (rs6311: T) marker were protective against suicidal behavior.

The complementary makers (rs594242-rs6311: G-C and rs6311: C) were associated with increased risk for non-violent and impulsive suicidal behavior. Furthermore, CC-homozygotes for the functional SNP rs6311 reported more anger- and aggression-related behavior.


[PMID 17590256] 5-HT2A SNPs and the Temperament and Character Inventory.


[PMID 18439448OA-icon.png] Stress, genes and the biology of suicidal behavior.