rs619203

minus

Geno	Mag	Summary
(C;C)
(C;G)	1.5	increases susceptibility to Myocardial Infarction 1.15 times
(G;G)		None

Reference

GRCh38 38.1/141

Chromosome

6

Position

117301021

Gene

ROS1

is a	snp
is	mentioned by
dbSNP	rs619203
dbSNP (classic)	rs619203
ClinGen	rs619203
ebi	rs619203
HLI	rs619203
Exac	rs619203
Gnomad	rs619203
Varsome	rs619203
LitVar	rs619203
Map	rs619203
PheGenI	rs619203
Biobank	rs619203
1000 genomes	rs619203
hgdp	rs619203
ensembl	rs619203
geneview	rs619203
scholar	rs619203
google	rs619203
pharmgkb	rs619203
gwascentral	rs619203
openSNP	rs619203
23andMe	rs619203
SNPshot	rs619203
SNPdbe	rs619203
MSV3d	rs619203
GWAS Ctlg	rs619203

GMAF

0.1598

Max Magnitude

1.5

?

(C;C) (C;G) (G;G)

28

The G->C (Cys2229Ser) polymorphism (rs619203) of the ROS1 gene was significantly associated with atherothrombotic cerebral infarction in a study of 3,400+ Japanese adults.[PMID 18566305]

An independent study of 3657 patients with myocardial infarction (885 women and 2772 men) and 1211 control individuals (598 women and 613 men) did not observe any correlation to this SNP.[PMID 19709766]

rs619203 increases susceptibility to Myocardial Infarction 1.15 times for heterozygotes (CG) and 1.75 times for homozygotes (TT) [PMID 16175505 ]

[PMID 22856164] [Evaluation of association between 9 genetic polymorphism and myocardial infarction in the Siberian population]

[PMID 18599554 ] Replication study of 10 genetic polymorphisms associated with coronary heart disease in a specific high-risk population with familial hypercholesterolemia.

[PMID 19863298] ROS1 Asp2213Asn polymorphism is not associated with coronary artery disease in a Greek case-control study.

[PMID 24087953] [Genetic predictors of myocardial infarction in subjects of young age]