rs6707530
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (G;G) | 1.1 | in colorectal cancer, may allow cancer cells to invade deeper layers |
| Make rs6707530(G;T) |
| Make rs6707530(T;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 2 |
| Position | 215375861 |
| Gene | FN1 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs6707530 |
| dbSNP (classic) | rs6707530 |
| ClinGen | rs6707530 |
| ebi | rs6707530 |
| HLI | rs6707530 |
| Exac | rs6707530 |
| Gnomad | rs6707530 |
| Varsome | rs6707530 |
| LitVar | rs6707530 |
| Map | rs6707530 |
| PheGenI | rs6707530 |
| Biobank | rs6707530 |
| 1000 genomes | rs6707530 |
| hgdp | rs6707530 |
| ensembl | rs6707530 |
| geneview | rs6707530 |
| scholar | rs6707530 |
| rs6707530 | |
| pharmgkb | rs6707530 |
| gwascentral | rs6707530 |
| openSNP | rs6707530 |
| 23andMe | rs6707530 |
| SNPshot | rs6707530 |
| SNPdbe | rs6707530 |
| MSV3d | rs6707530 |
| GWAS Ctlg | rs6707530 |
| Max Magnitude | 1.1 |
| ? | (G;G) (G;T) (T;T) | 28 |
|---|---|---|
|
| ||
[PMID 24919860] A single nucleotide polymorphism in fibronectin 1 determines tumor shape in colorectal cancer. (2014 article) "SNP analysis indicated that 44 tumors with a GG genotype at SNP rs6707530 showed significantly higher FN1 expression than did 23 tumors with GT/TT genotypes (p<0.05). The product of the FN1 gene (located at 2q34) is involved in cell adhesion, migration and metastasis in mesenchymal tumors. Abundant expression of FN1 may allow cancer cells to invade deeper layers, which would eventually define tumor shape." (Abstract)
