rs7753394
From SNPedia
Orientation | plus |
Stabilized | plus |
Geno | Mag | Summary |
---|---|---|
(C;C) | 1.5x risk of Crohn's disease | |
(C;T) | 1.2x risk of Crohn's disease | |
(T;T) | 0 | normal |
Reference | GRCh38 38.1/141 |
Chromosome | 6 |
Position | 137764111 |
is a | snp |
is | mentioned by |
dbSNP | rs7753394 |
dbSNP (classic) | rs7753394 |
ClinGen | rs7753394 |
ebi | rs7753394 |
HLI | rs7753394 |
Exac | rs7753394 |
Gnomad | rs7753394 |
Varsome | rs7753394 |
LitVar | rs7753394 |
Map | rs7753394 |
PheGenI | rs7753394 |
Biobank | rs7753394 |
1000 genomes | rs7753394 |
hgdp | rs7753394 |
ensembl | rs7753394 |
geneview | rs7753394 |
scholar | rs7753394 |
rs7753394 | |
pharmgkb | rs7753394 |
gwascentral | rs7753394 |
openSNP | rs7753394 |
23andMe | rs7753394 |
SNPshot | rs7753394 |
SNPdbe | rs7753394 |
MSV3d | rs7753394 |
GWAS Ctlg | rs7753394 |
GMAF | 0.4343 |
Max Magnitude | 0 |
? | (C;C) (C;T) (T;T) | 28 |
---|---|---|
|
rs7753394 has been reported in a large study to be associated with Crohn's disease.
The risk allele (oriented to the dbSNP entry) is (C); the odds ratio associated with heterozygotes is 1.21 (CI 1.04-1.40), and for homozygotes, 1.48 (CI 1.25-1.76). [PMID 17554300]
[PMID 18438406] Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease.
[PMID 19956648] Pathway analysis of GWAS provides new insights into genetic susceptibility to 3 inflammatory diseases.