rs80359335

plus

Geno	Mag	Summary
(-;-)	0	common in clinvar
(-;A)	6	BRCA2 variant considered pathogenic for breast cancer

Make rs80359335(A;A)

Reference

GRCh38 38.1/142

Chromosome

13

Position

32336937

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs80359335
dbSNP (classic)	rs80359335
ClinGen	rs80359335
ebi	rs80359335
HLI	rs80359335
Exac	rs80359335
Gnomad	rs80359335
Varsome	rs80359335
LitVar	rs80359335
Map	rs80359335
PheGenI	rs80359335
Biobank	rs80359335
1000 genomes	rs80359335
hgdp	rs80359335
ensembl	rs80359335
geneview	rs80359335
scholar	rs80359335
google	rs80359335
pharmgkb	rs80359335
gwascentral	rs80359335
openSNP	rs80359335
23andMe	rs80359335
SNPshot	rs80359335
SNPdbe	rs80359335
MSV3d	rs80359335
GWAS Ctlg	rs80359335

Merged from

Rs606231399, Rs80359338

Max Magnitude

6

rs80359335, also known as c.2588dupA, 2810insA, c.2582_2583insA and p.Gln861?fs, is a variant in the BRCA2 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs80359335(A;A)
Alt	rs80359335(A;A)
Reference	Rs80359335(-;-)
Significance	Pathogenic
Disease	Breast-ovarian cancer Hereditary breast and ovarian cancer syndrome Hereditary cancer-predisposing syndrome not provided
Variation	info
Gene	BRCA2
CLNDBN	Breast-ovarian cancer, familial 2 Hereditary breast and ovarian cancer syndrome Hereditary cancer-predisposing syndrome not provided
Reversed	0
HGVS	NC_000013.10:g.32911080dupA
CLNSRC	Breast Cancer Information Core (BRCA2)
CLNACC	RCV000031374.12, RCV000044019.4, RCV000218358.1, RCV000296013.1,