rs80359525

plus

Geno	Mag	Summary
(-;AGTAA)	6	BRCA2 variant considered pathogenic for breast cancer
(AGTAA;AGTAA)	0	common in clinvar

Make rs80359525(-;-)

Reference

GRCh38 38.1/141

Chromosome

13

Position

32339971

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs80359525
dbSNP (classic)	rs80359525
ClinGen	rs80359525
ebi	rs80359525
HLI	rs80359525
Exac	rs80359525
Gnomad	rs80359525
Varsome	rs80359525
LitVar	rs80359525
Map	rs80359525
PheGenI	rs80359525
Biobank	rs80359525
1000 genomes	rs80359525
hgdp	rs80359525
ensembl	rs80359525
geneview	rs80359525
scholar	rs80359525
google	rs80359525
pharmgkb	rs80359525
gwascentral	rs80359525
openSNP	rs80359525
23andMe	rs80359525
SNPshot	rs80359525
SNPdbe	rs80359525
MSV3d	rs80359525
GWAS Ctlg	rs80359525

Max Magnitude

6

rs80359525, also known as 5844del5, c.5616_5620delAGTAA and p.Lys1872_Ile1874?fs, is a variant in the BRCA2 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs80359525(-;-)
Alt	rs80359525(-;-)
Reference	Rs80359525(AGTAA;AGTAA)
Significance	Pathogenic
Disease	not provided Breast-ovarian cancer Hereditary cancer-predisposing syndrome Hereditary breast and ovarian cancer syndrome Familial cancer of breast
Variation	info
Gene	BRCA2
CLNDBN	not provided Breast-ovarian cancer, familial 2 Hereditary cancer-predisposing syndrome Hereditary breast and ovarian cancer syndrome Familial cancer of breast
Reversed	0
HGVS	NC_000013.10:g.32914108_32914112delAGTAA
CLNSRC	Breast Cancer Information Core (BRCA2)
CLNACC	RCV000044697.6, RCV000077356.6, RCV000131113.3, RCV000195403.2, RCV000473703.1,