rs8179181

Orientation

minus

Stabilized

minus

Geno	Mag	Summary
(C;C)	0	common in clinvar

Make rs8179181(C;T)

Make rs8179181(T;T)

Reference

GRCh38 38.1/141

Chromosome

19

Position

41332301

Gene

TGFB1

is a	snp
is	mentioned by
dbSNP	rs8179181
dbSNP (classic)	rs8179181
ClinGen	rs8179181
ebi	rs8179181
HLI	rs8179181
Exac	rs8179181
Gnomad	rs8179181
Varsome	rs8179181
LitVar	rs8179181
Map	rs8179181
PheGenI	rs8179181
Biobank	rs8179181
1000 genomes	rs8179181
hgdp	rs8179181
ensembl	rs8179181
geneview	rs8179181
scholar	rs8179181
google	rs8179181
pharmgkb	rs8179181
gwascentral	rs8179181
openSNP	rs8179181
23andMe	rs8179181
SNPshot	rs8179181
SNPdbe	rs8179181
MSV3d	rs8179181
GWAS Ctlg	rs8179181

GMAF

0.1056

Max Magnitude

0

?	(C;C) (C;T) (T;T)	28

OMIM	190180
Desc	TRANSFORMING GROWTH FACTOR, BETA-1; TGFB1
Variant
Related	also

OMIM	219700
Desc
Variant
Related	also

[PMID 15113403] Current limitations of SNP data from the public domain for studies of complex disorders: a test for ten candidate genes for obesity and osteoporosis.

[PMID 15157284] Patterns of linkage disequilibrium and haplotype distribution in disease candidate genes.

[PMID 17333284] Genetic polymorphisms in transforming growth factor beta-1 (TGFB1) and childhood asthma and atopy.

[PMID 17686149] Xenobiotic metabolizing enzyme gene polymorphisms predict response to lung volume reduction surgery.

[PMID 18424453] Interaction between a novel TGFB1 haplotype and CFTR genotype is associated with improved lung function in cystic fibrosis.

[PMID 19299629] Sequencing of TGF-beta pathway genes in familial cases of intracranial aneurysm.

ClinVar
Risk	rs8179181(A;A) rs8179181(G;G) rs8179181(T;T)
Alt	rs8179181(A;A) rs8179181(G;G) rs8179181(T;T)
Reference	Rs8179181(C;C)
Significance	Non-pathogenic
Disease	not specified
Variation	info
Gene	TGFB1
CLNDBN	not specified
Reversed	1
HGVS	NC_000019.9:g.41838206G>A
CLNSRC
CLNACC	RCV000247364.1,

[PMID 29183791] Transforming growth factor beta 1 related gene polymorphisms in gestational hypertension and preeclampsia: A case-control candidate gene association study.