rs910080

plus

Geno	Mag	Summary
(A;A)	0	common in clinvar

Make rs910080(A;G)

Make rs910080(G;G)

Reference

GRCh38 38.1/141

Chromosome

20

Position

1979580

Gene	LOC727993, PDYN

is a	snp
is	mentioned by
dbSNP	rs910080
dbSNP (classic)	rs910080
ClinGen	rs910080
ebi	rs910080
HLI	rs910080
Exac	rs910080
Gnomad	rs910080
Varsome	rs910080
LitVar	rs910080
Map	rs910080
PheGenI	rs910080
Biobank	rs910080
1000 genomes	rs910080
hgdp	rs910080
ensembl	rs910080
geneview	rs910080
scholar	rs910080
google	rs910080
pharmgkb	rs910080
gwascentral	rs910080
openSNP	rs910080
23andMe	rs910080
SNPshot	rs910080
SNPdbe	rs910080
MSV3d	rs910080
GWAS Ctlg	rs910080

GMAF

0.4669

Max Magnitude

0

?

(A;A) (A;G) (G;G)

28

[PMID 18923396 ] In Caucasians, we found point-wise significant associations of 3' UTR SNPs (rs910080, rs910079, and rs2235749) with cocaine dependence and cocaine/alcohol codependence.

[PMID 19468819] Gene polymorphisms in prodynorphin (PDYN) are associated with episodic memory in the elderly

[PMID 21382455] Association between heroin dependence and prodynorphin gene polymorphisms

[PMID 22443215] Genetic association analyses of PDYN polymorphisms with heroin and cocaine addiction.

[PMID 23101464 ] Association of the PDYN gene with alcohol dependence and the propensity to drink in negative emotional states

[PMID 27074815 ] A Functional 3'UTR Polymorphism (rs2235749) of Prodynorphin Alters microRNA-365 Binding in Ventral Striatonigral Neurons to Influence Novelty Seeking and Positive Reward Traits

[PMID 28656735] An analysis of genetic association in opioid dependence susceptibility.

ClinVar
Risk	rs910080(G;G)
Alt	rs910080(G;G)
Reference	Rs910080(A;A)
Significance	Non-pathogenic
Disease	Spinocerebellar Ataxia
Variation	info
Gene	PDYN LOC727993
CLNDBN	Spinocerebellar Ataxia, Dominant
Reversed	0
HGVS	NC_000020.10:g.1960226A>G
CLNSRC
CLNACC	RCV000263533.1,