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rs966423

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(C;C) 2 Possible elevated thyroid cancer risk
(C;T) 2 Possible elevated thyroid cancer risk
Make rs966423(T;T)
ReferenceGRCh38 38.1/141
Chromosome2
Position217445617
GeneDIRC3
is asnp
is mentioned by
dbSNPrs966423
dbSNP (classic)rs966423
ClinGenrs966423
ebirs966423
HLIrs966423
Exacrs966423
Gnomadrs966423
Varsomers966423
LitVarrs966423
Maprs966423
PheGenIrs966423
Biobankrs966423
1000 genomesrs966423
hgdprs966423
ensemblrs966423
geneviewrs966423
scholarrs966423
googlers966423
pharmgkbrs966423
gwascentralrs966423
openSNPrs966423
23andMers966423
SNPshotrs966423
SNPdbers966423
MSV3drs966423
GWAS Ctlgrs966423
GMAF0.3696
Max Magnitude2
? (C;C) (C;T) (T;T) 28


GWAS snp
PMID [PMID 22267200OA-icon.png]
Trait
Title Discovery of common variants associated with low TSH levels and thyroid cancer risk.
Risk Allele C
P-val 1E-9
Odds Ratio 1.3400 None


[PMID 19481195OA-icon.png] The primordial growth disorder 3-M syndrome connects ubiquitination to the cytoskeletal adaptor OBSL1.


[PMID 23659773OA-icon.png] Cumulative Risk Impact of Five Genetic Variants Associated With Papillary Thyroid Carcinoma


[PMID 23847140] Confirmation of papillary thyroid cancer susceptibility loci identified by genome-wide association studies of chromosomes 14q13, 9q22, 2q35 and 8p12 in a Chinese population


[PMID 24591304OA-icon.png] Significant SNPs have limited prediction ability for thyroid cancer


[PMID 25746573] Clinical significance of papillary thyroid cancer risk loci identified by genome-wide association studies


[PMID 26490305] Association Between GWAS-derived rs966423 Genetic Variant and Overall Mortality in Patients with Differentiated Thyroid Cancer


[PMID 31681970] Clinical implications of GWAS variants associated with differentiated thyroid cancer.