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Leprosy

From SNPedia

Leprosy was formerly a dreaded infectious disease whose victims were ostracized, but it can now be treated and cured. The 23andMe blog reports that the following SNPs are associated with altered risk of leprosy in people of Asian descent: The blog is based on the scientific article

[PMID 20018961OA-icon.png] Genomewide association study of leprosy.


Some other SNPs associated to leprosy, according to the GWAS catalogː

SNPs in these genes are associated with susceptibility to leprosy [1] and other diseases:

Publications[edit]

[PMID 27238287] Erratum to "Integrative analyses of leprosy susceptibility genes indicate a common autoimmune profile" [J. Dermatol. Sci. 82 (2016) 18-27.

[PMID 26844546OA-icon.png] A Missense LRRK2 Variant Is a Risk Factor for Excessive Inflammatory Responses in Leprosy.

[PMID 26805555] Integrative analyses of leprosy susceptibility genes indicate a common autoimmune profile.

[PMID 26793196OA-icon.png] Gene Association with Leprosy: A Review of Published Data.

[PMID 25642632] Discovery of six new susceptibility loci and analysis of pleiotropic effects in leprosy.

[PMID 25521227] Association of the LRRK2 genetic polymorphisms with leprosy in Han Chinese from Southwest China.

[PMID 25432815OA-icon.png] Genetics of leprosy: Expected-and unexpected-developments and perspectives.

[PMID 25367361OA-icon.png] NOD2 and CCDC122-LACC1 genes are associated with leprosy susceptibility in Brazilians.

[PMID 22984114OA-icon.png] Crohn's disease susceptibility genes are associated with leprosy in the Vietnamese population.

[PMID 22019778OA-icon.png] Identification of two new loci at IL23R and RAB32 that influence susceptibility to leprosy.

[PMID 21119019OA-icon.png] Leprosy and the human genome.

[PMID 20936290OA-icon.png] Leprosy as a genetic disease.

[PMID 20018961OA-icon.png] Genomewide association study of leprosy.