Have questions? Visit https://www.reddit.com/r/SNPedia

rs10033464(T;T)

From SNPedia

1.4x increased risk of Atrial Fibrillation and cardioembolic stroke
Is agenotype
ofrs10033464
Gene
Chromosome4
Position110,799,605
mentionedby
Magnitude3
ReputeBad
Geno Mag Summary
(G;G) 1.9 0.92x decreased risk of Atrial Fibrillation and cardioembolic stroke.
(G;T) 3 1.28x increased risk of Atrial Fibrillation and cardioembolic stroke.
(T;T) 3 1.4x increased risk of Atrial Fibrillation and cardioembolic stroke

Two copies of the mutant version which makes affects the formation of the heart and makes people more likely to get Atrial Fibrillation (quivering of the top chambers of the heart caused by chaotic electrical signals) and more likely to have a cardioembolic stroke (blocked blood flow to the brain). But also check the other SNP nearby (rs2200733) which affects Atrial Fibrillation even more. 23andMe gave this a 4 star confidence rating as it has been heavily studied. It has been confirmed in Europeans.