Have questions? Visit https://www.reddit.com/r/SNPedia

rs13306435

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(T;T) 0 common in complete genomics
Make rs13306435(A;A)
Make rs13306435(A;T)
ReferenceGRCh38 38.1/141
Chromosome7
Position22731420
GeneIL6
is asnp
is mentioned by
dbSNPrs13306435
ebirs13306435
HLIrs13306435
Exacrs13306435
Varsomers13306435
Maprs13306435
PheGenIrs13306435
hapmaprs13306435
1000 genomesrs13306435
hgdprs13306435
ensemblrs13306435
gopubmedrs13306435
geneviewrs13306435
scholarrs13306435
googlers13306435
pharmgkbrs13306435
gwascentralrs13306435
openSNPrs13306435
23andMers13306435
23andMe allrs13306435
SNP Nexus

SNPshotrs13306435
SNPdbers13306435
MSV3drs13306435
GWAS Ctlgrs13306435
GMAF0.0303
Max Magnitude0
? (A;A) (A;T) (T;T) 28

A haplotype of the IL6 gene appears to be overrepresented in sciatica patients.[PMID 15733644, PMID 18321738]. The haplotype consists of SNPs rs1800797-rs1800796- rs1800795-rs13306435.


[PMID 18496509OA-icon.png] An IL-6 haplotype on human chromosome 7p21 confers risk for impaired renal function in type 2 diabetic patients.


[PMID 19164257] Effects of interleukin-6 T15A single nucleotide polymorphism on baseline peritoneal solute transport rate in incident peritoneal dialysis patients.


[PMID 19387461OA-icon.png] Interleukin-6 haplotypes and the response to therapy of chronic hepatitis C virus infection.


[PMID 19503017OA-icon.png] Genetic ancestry modifies pharmacogenetic gene-gene interaction for asthma.


GET Evidence
IL6-D162E
aa_change Asp162Glu
aa_change_short D162E
impact not reviewed
qualified_impact Insufficiently evaluated not reviewed
overall_frequency 0.00762223
summary



[PMID 22714907] IL6 gene polymorphisms and susceptibility to colorectal cancer: a meta-analysis and review.