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rs2184026

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(C;C) 0 common in complete genomics
Make rs2184026(C;T)
Make rs2184026(T;T)
ReferenceGRCh38 38.1/141
Chromosome9
Position98542066
GeneGABBR2
is asnp
is mentioned by
dbSNPrs2184026
ebirs2184026
HLIrs2184026
Exacrs2184026
Varsomers2184026
Maprs2184026
PheGenIrs2184026
hapmaprs2184026
1000 genomesrs2184026
hgdprs2184026
ensemblrs2184026
gopubmedrs2184026
geneviewrs2184026
scholarrs2184026
googlers2184026
pharmgkbrs2184026
gwascentralrs2184026
openSNPrs2184026
23andMers2184026
23andMe allrs2184026
SNP Nexus

SNPshotrs2184026
SNPdbers2184026
MSV3drs2184026
GWAS Ctlgrs2184026
GMAF0.2938
Max Magnitude0
? (C;C) (C;T) (T;T) 28
[PMID 15759211OA-icon.png] Associated with nicotine Dependence as part of several haplotypes, based on a study of 1,000+ subjects including both African-Americans and European-Americans.

The risk haplotype varies between populations. Among African-Americans, the haplotype C-C-G of rs2491397-rs2184026-rs3750344 had a significant positive association with nicotine dependence. Among European-Americans, for rs1435252-rs3780422-rs2779562-rs3750344, the C-A-C-A haplotype was positively associated with nicotine dependence while the T-A-T-A haplotype was negatively associated.[PMID 15759211OA-icon.png]

OMIM607340
DescGAMMA-AMINOBUTYRIC ACID B RECEPTOR 2; GABBR2
Variant
Relatedalso
OMIM607340
Desc
Variant0001
Relatedalso


ClinVar
Risk rs2184026(T;T)
Alt rs2184026(T;T)
Reference rs2184026(C;C)
Significance Other
Disease Tobacco addiction
Variation info
Gene GABBR2
CLNDBN Tobacco addiction, susceptibility to
Reversed 0
HGVS NC_000009.11:g.101304348C\x3d
CLNSRC ClinVar
CLNACC RCV000003495.1,