Rs3750344

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is asnp
is mentioned by
dbSNPrs3750344
hapmaprs3750344
hgdprs3750344
ensemblrs3750344
gopubmedrs3750344
scholarrs3750344
googlers3750344
pharmgkbrs3750344
hgvbaseg2prs3750344
medrefsnprs3750344
23andMers3750344
SNP Nexus

GeneGABAB2
Chromosome9
Orientationminus
Position100380136
GenotypeEffect
rs3750344(A;A)*?
rs3750344(A;G)*?
rs3750344(G;G)*?


[PMID 15759211] Associated with Nicotine Dependence as part of several haplotypes, based on a study of 1,000+ subjects including both African-Americans and European-Americans.

Interestingly, the risk allele varies between populations. Among African-Americans, the haplotype C-C-G of rs2491397-rs2184026-rs3750344 had a significant positive association with nicotine dependence. Among European-Americans, for rs1435252-rs3780422-rs2779562-rs3750344, the C-A-C-A haplotype was positively associated with nicotine dependence while the T-A-T-A haplotype was negatively associated.[PMID 15759211]

? (A;A) (A;G) (G;G)
Related to GAMMA-AMINOBUTYRIC ACID B RECEPTOR 2; GABBR2 according to omim 607340. See also