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rs4149056(C;C)

From SNPedia

17x myopathy risk for statin users
Is agenotype
ofrs4149056
GeneSLCO1B1
Chromosome12
Position21,178,615
mentionedby
Magnitude3.2
ReputeBad
Geno Mag Summary
(C;C) 3.2 17x myopathy risk for statin users
(C;T) 2.1 reduced breakdown of some drugs; 5x increased myopathy risk for statin users
(T;T) 0 normal

reduced breakdown of some drugs;

significantly associated with myopathy in patients who received simvastatin, but not in patients who received atorvastatin. [PMID 21243006]

[PMID 21851379] however it did not affect pravastatin.