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rs671(A;A)

From SNPedia

Asian Flusher; increased risk of esophageal cancer; East Asian ancestry; Disulfiram not effective for alcoholism.
Is agenotype
ofrs671
GeneALDH2
Chromosome12
Position111,803,962
mentionedby
Magnitude4
ReputeBad
Geno Mag Summary
(A;A) 4 Asian Flusher; increased risk of esophageal cancer; East Asian ancestry; Disulfiram not effective for alcoholism.
(A;G) 3.5 Asian Flush; worse hangovers; increased risk of esophageal cancer; East Asian ancestry; Disulfiram probably not effective for alcoholism.
(G;G) 2 Alcohol Flush: Normal, doesn't flush. Normal hangovers. Normal risk of Alcoholism. Normal risk of Esophageal Cancer. Disulfiram is effective for alcoholism.

People with this genotype will experience the asian flush, a redness in the face when drinking alcohol. Unable to break down acetaldehyde, a toxic byproduct of alcohol and cigarette smoke. As a result, you are likely to have greatly increased odds of esophageal cancer, especially if you drink or smoke. It also causes worse hangovers. On the bright side, that makes you much less likely to become an alcoholic. If you become an alcoholic anyway, disulfiram (Antabuse) will not be an effective treatment.