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rs7193144

From SNPedia

Orientationplus
Stabilizedplus
Make rs7193144(C;C)
Make rs7193144(C;T)
Make rs7193144(T;T)
ReferenceGRCh38 38.1/141
Chromosome16
Position53776774
GeneFTO
is asnp
is mentioned by
dbSNPrs7193144
ebirs7193144
HLIrs7193144
Exacrs7193144
Varsomers7193144
Maprs7193144
PheGenIrs7193144
hapmaprs7193144
1000 genomesrs7193144
hgdprs7193144
ensemblrs7193144
gopubmedrs7193144
geneviewrs7193144
scholarrs7193144
googlers7193144
pharmgkbrs7193144
gwascentralrs7193144
openSNPrs7193144
23andMers7193144
23andMe allrs7193144
SNP Nexus

SNPshotrs7193144
SNPdbers7193144
MSV3drs7193144
GWAS Ctlgrs7193144
GMAF0.331
Max Magnitude
? (C;C) (C;T) (T;T) 28

This SNP is in a linkage block in the FTO gene with rs1121980; see rs1121980 for the association of this block with early onset obesity since it showed the strongest association.[PMID 18159244OA-icon.png] The risk allele is C.


[PMID 18379722OA-icon.png] Variations in the FTO gene are associated with severe obesity in the Japanese.


[PMID 18445669] Lack of association of fatness-related FTO gene variants with energy expenditure or physical activity.


[PMID 18487448OA-icon.png] Common variation in the fat mass and obesity-associated (FTO) gene confers risk of obesity and modulates BMI in the Chinese population.


[PMID 18599522OA-icon.png] FTO variants are associated with obesity in the Chinese and Malay populations in Singapore.


[PMID 19005641OA-icon.png] FTO gene variants are strongly associated with type 2 diabetes in South Asian Indians.


[PMID 19008344OA-icon.png] Association analysis of variation in/near FTO, CDKAL1, SLC30A8, HHEX, EXT2, IGF2BP2, LOC387761, and CDKN2B with type 2 diabetes and related quantitative traits in Pima Indians.


[PMID 20017965OA-icon.png] Identifying association under a previous linkage peak on chromosome 16 for body mass index using cross-sectional and longitudinal data of the Framingham Heart Study.


[PMID 21175269] Genetic variations in the FTO gene are associated with type 2 diabetes and obesity in south Indians (CURES-79).