rs1801133(C;T)

1 copy of C677T allele of MTHFR = 65% efficiency in processing folic acid

Is a	genotype
of	rs1801133
Gene	MTHFR
Chromosome	1
Position	11,796,321
Merged from	Rs59514310
mentioned	by

Magnitude

2.2

Repute

Bad

Geno	Mag	Summary
(C;C)	0	Common genotype: normal homocysteine levels
(C;T)	2.2	1 copy of C677T allele of MTHFR = 65% efficiency in processing folic acid
(T;T)	2.8	homozygous for C677T of MTHFR = 10-20% efficiency in processing folic acid = high homocysteine, low B12 and folate levels

It is found in approximately

• 48% of Hispanic Americans
• 45% of Caucasian Americans
• 45% of Japanese
• 37% of Germans
• 29% of Asians
• 24% of African Americans
• 12% of Sub-Saharan Africans