HLA-C
From SNPedia
| is a | gene |
| is | mentioned by |
| Full name | major histocompatibility complex, class I, C |
| EntrezGene | 3107 |
| PheGenI | 3107 |
| VariationViewer | 3107 |
| ClinVar | HLA-C |
| GeneCards | HLA-C |
| dbSNP | 3107 |
| Diseases | HLA-C |
| SADR | 3107 |
| HugeNav | 3107 |
| wikipedia | HLA-C |
| HLA-C | |
| gopubmed | HLA-C |
| EVS | HLA-C |
| HEFalMp | HLA-C |
| MyGene2 | HLA-C |
| 23andMe | HLA-C |
| UniProt | P10321 |
| Ensembl | ENSG00000204525 |
| OMIM | 142840 |
| # SNPs | 531 |
| Max Magnitude | Chromosome position | Summary | |
|---|---|---|---|
| rs1049650 | 0 | 31,269,031 | |
| rs1049663 | 0 | 31,269,036 | |
| rs1049668 | 0 | 31,269,044 | |
| rs1049709 | 0 | 31,269,077 | |
| rs1049724 | 0 | 31,269,085 | |
| rs1049853 | 0 | 31,269,123 | |
| rs1050105 | 0 | 31,269,992 | |
| rs1050106 | 0 | 31,269,994 | |
| rs1050118 | 0 | 31,269,999 | |
| rs1050147 | 0 | 31,270,025 | |
| rs1050180 | 0 | 31,270,056 | |
| rs1050276 | 0 | 31,270,291 | |
| rs1050317 | 0 | 31,270,358 | |
| rs1050320 | 0 | 31,270,361 | |
| rs1050326 | 0 | 31,270,370 | |
| rs1050328 | 0 | 31,270,378 | |
| rs1050343 | 0 | 31,270,455 | |
| rs1050344 | 0 | 31,270,457 | |
| rs1050357 | 0 | 31,271,103 | |
| rs1050366 | 0 | 31,271,180 | |
| rs1050371 | 0 | 31,271,233 | |
| rs1050373 | 0 | 31,271,239 | |
| rs1050384 | 0 | 31,271,305 | |
| rs1050685 | 0 | 31,271,133 | |
| rs1050686 | 0 | 31,271,132 | |
| rs1050716 | 0 | 31,270,453 | |
| rs1065406 | 0 | 31,271,272 | |
| rs1065600 | 0 | 31,270,058 | |
| rs1065711 | 0 | 31,269,076 | |
| rs1071649 | 0 | 31,271,337 | |
| rs1130838 | 0 | 31,269,347 | |
| rs1130935 | 0 | 31,269,990 | |
| rs1130947 | 0 | 31,269,996 | |
| rs1131014 | 0 | 31,270,232 | |
| rs1131015 | 0 | 31,270,233 | |
| rs1131096 | 0 | 31,270,482 | |
| rs1131103 | 0 | 31,271,091 | |
| rs1131104 | 0 | 31,271,098 | |
| rs1131114 | 0 | 31,271,323 | |
| rs1131115 | 0 | 31,271,324 | |
| rs1131118 | 0 | 31,271,331 | |
| rs1131119 | 0 | 31,271,339 | |
| rs1131122 | 0 | 31,271,599 | |
| rs1131123 | 0 | 31,271,601 | |
| rs1131292 | 0 | 31,270,469 | |
| rs114343571 | 0 | 31,270,788 | |
| rs1143551 | 0 | 31,269,983 | |
| rs11547346 | 0 | 31,271,569 | |
| rs11547350 | 0 | 31,271,191 | |
| rs11547351 | 0 | 31,271,646 | |
| ... further results | |||
HLA-C(PSORS1), a gene/antigen member of the HLA family is associated with immune conditions. Over 300 alleles have been documented, with 44 common.
Variants are correlated with susceptibility to Psoriasis (HLA-Cw6 interaction with CDSN*TTC) and HIV (-35C-T, rs9264942).
HLA-C1 interaction with KIR2DL2 affects HSV-1 susceptibility.
HLA-C*05 may protect against MS.
Tag SNPs for HLA-C antitypes on the 1M Illumina chip[edit]
| HLA | SNP | r2 | HLA_FRQ | SNP_FRQ |
|---|---|---|---|---|
| C*02:06 | rs3093671 | 0.006 | 0.000 | 0.03 |
| C*03:05 | rs3093561 | 0.003 | 0.000 | 0.01 |
| C*03:06 | rs2517490 | 0.007 | 0.000 | 0.02 |
| C*04:03 | rs2269713 | 0.039 | 0.003 | 0.04 |
| C*04:04 | rs2074475 | 0.006 | 0.000 | 0.02 |
| C*04:07 | rs7774197 | 0.003 | 0.000 | 0.05 |
| C*04:10 | rs3819284 | 0.010 | 0.000 | 0.02 |
| C*06:02 | rs10484554 | 0.11 | ||
| C*07:26 | rs9296020 | 0.009 | 0.000 | 0.01 |
| C*08:01 | rs2524083 | 0.071 | 0.010 | 0.12 |
| C*12:04 | rs28732150 | 0.015 | 0.001 | 0.05 |
| C*15:04 | rs16899178 | 0.031 | 0.002 | 0.05 |
| C*16:04 | rs7747738 | 0.059 | 0.002 | 0.03 |
| C*18:01 | rs7759127 | 0.015 | 0.002 | 0.12 |
