rs1131118
From SNPedia
| Orientation | minus |
| Stabilized | minus |
| Geno | Mag | Summary |
|---|---|---|
| (A;A) | 0 | common in clinvar |
| Make rs1131118(A;T) |
| Make rs1131118(T;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 6 |
| Position | 31271331 |
| Gene | HLA-C |
| is a | snp |
| is | mentioned by |
| dbSNP | rs1131118 |
| dbSNP (classic) | rs1131118 |
| ClinGen | rs1131118 |
| ebi | rs1131118 |
| HLI | rs1131118 |
| Exac | rs1131118 |
| Gnomad | rs1131118 |
| Varsome | rs1131118 |
| LitVar | rs1131118 |
| Map | rs1131118 |
| PheGenI | rs1131118 |
| Biobank | rs1131118 |
| 1000 genomes | rs1131118 |
| hgdp | rs1131118 |
| ensembl | rs1131118 |
| geneview | rs1131118 |
| scholar | rs1131118 |
| rs1131118 | |
| pharmgkb | rs1131118 |
| gwascentral | rs1131118 |
| openSNP | rs1131118 |
| 23andMe | rs1131118 |
| SNPshot | rs1131118 |
| SNPdbe | rs1131118 |
| MSV3d | rs1131118 |
| GWAS Ctlg | rs1131118 |
| Max Magnitude | 0 |
| ClinVar | |
|---|---|
| Risk | rs1131118(C;C) rs1131118(G;G) rs1131118(T;T) |
| Alt | rs1131118(C;C) rs1131118(G;G) rs1131118(T;T) |
| Reference | Rs1131118(A;A) |
| Significance | Histocompatibility |
| Disease | |
| Variation | info |
| Gene | HLA-C |
| CLNDBN | |
| Reversed | 1 |
| HGVS | NC_000006.11:g.31239108T>A; NC_000006.11:g.31239108T>C; NC_000006.11:g.31239108T>G |
| CLNSRC | |
| CLNACC | |
[PMID 16642438
] Sequence and haplotype analysis supports HLA-C as the psoriasis susceptibility 1 gene.
[PMID 33297781] HLA-Cw6 and other HLA-C alleles, as well as MICB-DT, DDX58 and TYK2 genetic variants associate with optimal response to anti-IL-17A treatment in patients with psoriasis.
