rs10947262
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | 1.3 | 1.3x increased risk for osteoarthritis |
| (T;T) | 0 |
| Make rs10947262(C;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 6 |
| Position | 32405535 |
| Gene | BTNL2, LOC101929163 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs10947262 |
| dbSNP (classic) | rs10947262 |
| ClinGen | rs10947262 |
| ebi | rs10947262 |
| HLI | rs10947262 |
| Exac | rs10947262 |
| Gnomad | rs10947262 |
| Varsome | rs10947262 |
| LitVar | rs10947262 |
| Map | rs10947262 |
| PheGenI | rs10947262 |
| Biobank | rs10947262 |
| 1000 genomes | rs10947262 |
| hgdp | rs10947262 |
| ensembl | rs10947262 |
| geneview | rs10947262 |
| scholar | rs10947262 |
| rs10947262 | |
| pharmgkb | rs10947262 |
| gwascentral | rs10947262 |
| openSNP | rs10947262 |
| 23andMe | rs10947262 |
| SNPshot | rs10947262 |
| SNPdbe | rs10947262 |
| MSV3d | rs10947262 |
| GWAS Ctlg | rs10947262 |
| GMAF | 0.1703 |
| Max Magnitude | 1.3 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
rs10947262(C) was found to be associated with increased risk for osteoarthritis among Japanese and Europeans, with an odds ratio of 1.32 (CI: 1.19-1.46, combined p = 6.73×10e-8). This SNP is also in linkage disequilibrium with rs7775228, which was found to be associated in Japanese with osteoarthritis.[PMID 20305777
]
| GWAS snp | |
|---|---|
| PMID | [PMID 20305777]
|
| Trait | Knee osteoarthritis |
| Title | New Sequence Variants in HLA Class II/III Region Associated with Susceptibility to Knee Osteoarthritis Identified by Genome-Wide Association Study |
| Risk Allele | T |
| P-val | 5E-9 |
| Odds Ratio | 1.31 [1.20-1.44] |
