rs11012732
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (A;A) | 0 | |
| (A;G) | 1.4 | 1.4x increased risk for meningioma |
| (G;G) | 2 | 2x increased risk for meningioma |
| Reference | GRCh38 38.1/142 |
| Chromosome | 10 |
| Position | 21541175 |
| Gene | MLLT10 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs11012732 |
| dbSNP (classic) | rs11012732 |
| ClinGen | rs11012732 |
| ebi | rs11012732 |
| HLI | rs11012732 |
| Exac | rs11012732 |
| Gnomad | rs11012732 |
| Varsome | rs11012732 |
| LitVar | rs11012732 |
| Map | rs11012732 |
| PheGenI | rs11012732 |
| Biobank | rs11012732 |
| 1000 genomes | rs11012732 |
| hgdp | rs11012732 |
| ensembl | rs11012732 |
| geneview | rs11012732 |
| scholar | rs11012732 |
| rs11012732 | |
| pharmgkb | rs11012732 |
| gwascentral | rs11012732 |
| openSNP | rs11012732 |
| 23andMe | rs11012732 |
| SNPshot | rs11012732 |
| SNPdbe | rs11012732 |
| MSV3d | rs11012732 |
| GWAS Ctlg | rs11012732 |
| GMAF | 0.2259 |
| Max Magnitude | 2 |
| ? | (A;A) (A;G) (G;G) | 28 |
|---|---|---|
|
| ||
rs11012732 is a SNP in the MLLT10 gene on ch 10p12.31.
A study of ~1,600 patients with meningioma, all of European ancestry, concluded that increased risk for the disease was associated with rs11012732(G) alleles. The odds ratio was 1.46 (p = 1.9 x 10e-14). A nearby SNP, rs12770228, was also linked to meningioma risk.[PMID 21804547
]
