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rs11206510

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(T;T) 0
Make rs11206510(C;C)
Make rs11206510(C;T)
ReferenceGRCh38 38.1/141
Chromosome1
Position55030366
is asnp
is mentioned by
dbSNPrs11206510
dbSNP (classic)rs11206510
ClinGenrs11206510
ebirs11206510
HLIrs11206510
Exacrs11206510
Gnomadrs11206510
Varsomers11206510
LitVarrs11206510
Maprs11206510
PheGenIrs11206510
Biobankrs11206510
1000 genomesrs11206510
hgdprs11206510
ensemblrs11206510
geneviewrs11206510
scholarrs11206510
googlers11206510
pharmgkbrs11206510
gwascentralrs11206510
openSNPrs11206510
23andMers11206510
SNPshotrs11206510
SNPdbers11206510
MSV3drs11206510
GWAS Ctlgrs11206510
GMAF0.1198
Max Magnitude0
? (C;C) (C;T) (T;T) 28


23andMe blog coronary artery disease and heart attack

SNP Risk Version Effect


[PMID 28330911OA-icon.png] Carriers of a 'protective' rs11206510(C) allele benefit from a lower risk (0.84x) of nonfatal myocardial infarction by taking long-chain (LC) n-3 (ω-3) polyunsaturated fatty acids (PUFAs), whereas noncarriers show no such benefit, based on a study of ~4000 individuals living in Costa Rica.

GWAS snp
PMID [PMID 21378990OA-icon.png]
Trait Coronary heart disease
Title Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease
Risk Allele T
P-val 9E-8
Odds Ratio 1.0800 [1.05-1.11]
GWAS snp
PMID [PMID 20864672OA-icon.png]
Trait LDL cholesterol
Title Genetic Variants Influencing Circulating Lipid Levels and Risk of Coronary Artery Disease
Risk Allele T
P-val 1E-10
Odds Ratio 0.03 [0.02-0.04] unit increase
GWAS snp
PMID [PMID 19198609OA-icon.png]
Trait Myocardial infarction (early onset)
Title Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants
Risk Allele T
P-val 1E-8
Odds Ratio 1.15 [1.10-1.21]
GWAS snp
PMID [PMID 19060906OA-icon.png]
Trait LDL cholesterol
Title Common variants at 30 loci contribute to polygenic dyslipidemia
Risk Allele C
P-val 4E-8
Odds Ratio 0.09 [0.05-0.13] SD decrease
GWAS snp
PMID [PMID 18193043OA-icon.png]
Trait LDL cholesterol
Title Newly identified loci that influence lipid concentrations and risk of coronary artery disease
Risk Allele T
P-val 3.9999999999999998E-11
Odds Ratio 3.04 [NR] mg/dl higher



[PMID 23380588] Association between PCSK9 and LDLR gene polymorphisms with coronary heart disease: case-control study and meta-analysis.

[PMID 23202125OA-icon.png] Large-scale association analysis identifies new risk loci for coronary artery disease.

[PMID 23098650] Impact of variants within seven candidate genes on statin treatment efficacy [PMID 22152955OA-icon.png] Genetic susceptibility to coronary heart disease in type 2 diabetes: 3 independent studies.

[PMID 20835900OA-icon.png] Genetics of diabetes complications.

[PMID 20699424OA-icon.png] Effects of PCSK9 genetic variants on plasma LDL cholesterol levels and risk of premature myocardial infarction in the Italian population

[PMID 20576952] Minor Allele C of Chromosome 1p32 Single Nucleotide Polymorphism rs11206510 Confers Risk of Ischemic Stroke in the Chinese Han Population [PMID 20018036OA-icon.png] Using a latent growth curve model for an integrative assessment of the effects of genetic and environmental factors on multiple phenotypes.

[PMID 19185284OA-icon.png] Common variation in the beta-carotene 15,15'-monooxygenase 1 gene affects circulating levels of carotenoids: a genome-wide association study.

[PMID 19956433OA-icon.png] Genetics of coronary artery disease: focus on genome-wide association studies.

[PMID 19951432OA-icon.png] Analysis of recently identified dyslipidemia alleles reveals two loci that contribute to risk for carotid artery disease.

[PMID 19750184OA-icon.png] Genome-wide association studies for atherosclerotic vascular disease and its risk factors.

[PMID 19435741OA-icon.png] Common lipid-altering gene variants are associated with therapeutic intervention thresholds of lipid levels in older people.

[PMID 19060911OA-icon.png] Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.

[PMID 19060910OA-icon.png] Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.

[PMID 18852197OA-icon.png] Metabolic and cardiovascular traits: an abundance of recently identified common genetic variants.

[PMID 18193044OA-icon.png] Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.



[PMID 24251769] LDL-c-linked SNPs are associated with LDL-c and myocardial infarction despite lipid-lowering therapy in patients with established vascular disease


[PMID 26266351OA-icon.png] Association of Zinc Finger, C3HC-Type Containing 1 (ZC3HC1) rs11556924 Genetic Variant With Hypertension in a Finnish Population, the TAMRISK Study