rs1746048
Orientation | plus |
Stabilized | plus |
Geno | Mag | Summary |
---|---|---|
(C;C) | 1.3 | 1.03 increased risk for coronary heart disease |
(C;T) | 1.8 | 0.94 decreased risk for coronary heart disease |
(T;T) | 2 | 0.85 decreased risk for coronary heart disease |
Reference | GRCh38 38.1/142 |
Chromosome | 10 |
Position | 44280376 |
is a | snp |
is | mentioned by |
dbSNP | rs1746048 |
dbSNP (classic) | rs1746048 |
ClinGen | rs1746048 |
ebi | rs1746048 |
HLI | rs1746048 |
Exac | rs1746048 |
Gnomad | rs1746048 |
Varsome | rs1746048 |
LitVar | rs1746048 |
Map | rs1746048 |
PheGenI | rs1746048 |
Biobank | rs1746048 |
1000 genomes | rs1746048 |
hgdp | rs1746048 |
ensembl | rs1746048 |
geneview | rs1746048 |
scholar | rs1746048 |
rs1746048 | |
pharmgkb | rs1746048 |
gwascentral | rs1746048 |
openSNP | rs1746048 |
23andMe | rs1746048 |
SNPshot | rs1746048 |
SNPdbe | rs1746048 |
MSV3d | rs1746048 |
GWAS Ctlg | rs1746048 |
GMAF | 0.2833 |
Max Magnitude | 2 |
? | (C;C) (C;T) (T;T) | 28 |
---|---|---|
|
23andMe blog coronary artery disease and heart attack
SNP Risk Version Effect
- rs646776 T 1.19
- rs17465637 C 1.14
- rs1746048 C 1.17
- rs6725887 C 1.17
- rs11206510 T 1.15
- rs3184504 T 1.13
- rs2306374 C 1.15
- rs3782886 C 1.44
GWAS snp | |
---|---|
PMID | [PMID 19198609] |
Trait | Myocardial infarction (early onset) |
Title | Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants |
Risk Allele | C |
P-val | 7E-9 |
Odds Ratio | 1.17 [1.11-1.24] |
GWAS snp | |
---|---|
PMID | [PMID 21378990] |
Trait | |
Title | Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease |
Risk Allele | C |
P-val | 3E-10 |
Odds Ratio | 1.0900 [1.07-1.13] |
[PMID 21415067] The novel atherosclerosis locus at 10q11 regulates plasma CXCL12 levels
[PMID 19956433] Genetics of coronary artery disease: focus on genome-wide association studies.
[PMID 20835900] Genetics of diabetes complications.
[PMID 23531450] Relationship between Chemokine (C-X-C motif) ligand 12 gene variant (rs1746048) and coronary heart disease: Case-control study and meta-analysis
[PMID 23666823] Genetic variants on chromosome 10q11.21 are associated with ischemic stroke in the northern Chinese Han population.
[PMID 25804320] Association Between Coronary Artery Disease Genetic Variants and Subclinical Atherosclerosis: an Association Study and Meta-analysis
[PMID 26324845] Association of chemokine CXC ligand 12 gene polymorphism (rs1746048) with cardiovascular mortality in patients with rheumatoid arthritis: results from the Norfolk Arthritis Register
[PMID 31862910] The CXCL12 SNPs and their haplotypes are associated with serum lipid traits.