rs1127354(A;C)
From SNPedia
| lower ITPA production; be aware if treated with mercaptopurine |
| Is a | genotype |
| of | rs1127354 |
| Gene | ITPA |
| Chromosome | 20 |
| Position | 3,213,196 |
| mentioned | by |
| Magnitude | 2 |
| Repute | Bad |
| Geno | Mag | Summary |
|---|---|---|
| (A;A) | 3.2 | Causative for ITPase deficiency; also, reduces risk of anemia due to ribivarin anti-hepatitis C virus therapy |
| (A;C) | 2 | lower ITPA production; be aware if treated with mercaptopurine |
| (C;C) | 0 | common in clinvar |
see discussion at rs1127354
