rs1142345(G;G)
From SNPedia
| possibly incapable of detoxifying certain drugs |
| Is a | genotype |
| of | rs1142345 |
| Gene | TPMT |
| Chromosome | 6 |
| Position | 18,130,687 |
| mentioned | by |
| Magnitude | 3.5 |
| Repute | Bad |
| Geno | Mag | Summary |
|---|---|---|
| (A;A) | 0 | common in clinvar |
| (A;G) | 3 | TPMT*3C . impaired drug metabolism |
| (G;G) | 3.5 | possibly incapable of detoxifying certain drugs |
poor drug metabolism of some medications.
potentially encoding a variant incapable of detoxifying byproducts of certain antineoplastic and immunosuppressant drugs.
http://blog.23andme.com/health-traits/do-you-know-how-youll-respond-to-thiopurine-medications/
