|| Lower prostate cancer risk?
|?|| (A;A) (A;G) (G;G) ||28|
identified as one of three HNF1B
gene SNPs associated with decreased risk for prostate cancer
in two large prospective studies
[PMID 18758462] prostate cancer rs4430796 and rs11649743 in multiple populations, with P = 1.7 x 10(-9)
|Desc||PROSTATE CANCER, HEREDITARY, 11; HPC11|
] Large-scale fine mapping of the HNF1B locus and prostate cancer risk
[PMID 19117981] Sequence variants at 22q13 are associated with prostate cancer risk.
[PMID 19168595] Common variants of hepatocyte nuclear factor 1beta are associated with type 2 diabetes in a Chinese population.
[PMID 19318432] Generalizability of associations from prostate cancer genome-wide association studies in multiple populations.
[PMID 19434657] Individual and cumulative effect of prostate cancer risk-associated variants on clinicopathologic variables in 5,895 prostate cancer patients.
[PMID 19549807] Prostate cancer risk associated loci in African Americans.
[PMID 20039378] Estimation of genotype relative risks from pedigree data by retrospective likelihoods.
[PMID 20569440] Alterations in LMTK2, MSMB and HNF1B gene expression are associated with the development of prostate cancer.
[PMID 21390317] Characterizing associations and SNP-environment interactions for GWAS-identified prostate cancer risk markers--results from BPC3.
[PMID 23405784] [Susceptibility to prostate cancer in Han Chinese: single nucleotide polymorphism analysis of 1 667 cases]